In this post you will learn why your mother was always right when she said "Eat your broccoli".
Last week I talked about nitric oxide which is a great precursor to today's topic: sulforaphane. These two totally different molecules play a key role in cardiovascular health, and in particular in lowering blood pressure.
Unlike nitric oxide which is a gas molecule produced in the body, sulforaphane is a phytonutrient found in foods that combat oxidative stress. It has antioxidant properties. Research studies have shown this antioxidant to be “significantly effective” in lowering blood pressure numbers.
Nitric oxide production and sulforaphane are a dynamic duo in the quest for lowering blood pressure. Both nitric oxide and sulforaphane fight oxidative stress. Reduction in nitric oxide leads to endothelial dysfunction causing oxidative stress. Oxidative stress is a leading driver of hypertension. (1.) Sulforaphane, when ingested consistently, leads to a smoother vascular muscle tissue and lower blood pressure due to sulforaphane triggering the up regulation of enzymes to produce nitric oxide.
Sulforaphane and the Microbiome
Sulforaphane, like nitric oxide, intersects with the microbiome (gut bacteria). Research recently found sulforaphane to be a chemical that is good for us. Sulforaphane is found mostly in broccoli. So mom was always had good reason when she asked you to "eat your broccoli”.
Sulforaphane positively impacts the microbiome in relation to the efficacy of absorption of blood pressure medications. When consumed, sulforaphane undergoes a chemical reaction that releases an antioxidant and anti-inflammatory compound known as Nrf2. This activation of Nrf2 triggers a cascade of beneficial effects in the body, including promoting the growth of beneficial bacteria in the gut and reducing the abundance of harmful or “bad” bacteria. By enhancing the diversity and balance of the microbiome, sulforaphane supports optimal digestive function and strengthens the gut barrier. Studies have shown that a healthier gut bacteria environment allows better absorption of Ace-inhibitor blood pressure medications which allow these medications to actually work (2.). The combined impact of sulforaphane on the microbiome and blood pressure highlights its potential as a valuable dietary component for promoting lower blood pressure numbers and overall well-being.
(Continue reading below to learn which foods have the most sulforaphane, and the many health benefits that come from eating these superfoods daily.)